Doctor MJ

COVID-19 is caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) which progresses to severe pneumonia in 10-15% of patients. The main complications are Acute Respiratory Distress (ARDS), multiple organ failure and intravascular coagulopathy. Low platelet count is related with : Severity of disease. Risk of mortality in intensive care. High scores on Multiple Organ Dysfunction Score (MODS), Simplified Acute Physiology Score (SAPS) II, Acute Physiology and Chronic Health Evaluation (APACHE) II. During an SARS outbreak, thrombocytopenia was found in 55% of patients and was suspected as a significant risk factor for mortality. This research is to study whether thrombocytopenia is associated with severe COVID-19 infection. Meta-analysis. All documents reporting information on the number or level of thrombocytopenia in patients with COVID-19 with the definition of clinically severe disease fall into the inclusion criteria for this meta-analysis. In 7 studies : Severe COVID-

Oxygen therapy is the administration of additional oxygen given to patients : Severe Acute Respiratory Infection. Respiratory distress. Hypoxemia. Shock with a SpO target > 94%. During oxygen therapy, SpO² monitoring must be carried out. Emergency signs that require oxygen therapy : SpO² < 94%. Obstruction or not breathing. Respiratory distress. Central cyanosis. Signs of shock (acral cold, Capilary Refill Time > 3 seconds, pulse is weak and fast). Loss of consciousness. Convulsions. Signs of dehydration (lethargy, skin tugor slows). Algorithm for enhancing supportive respiratory therapy. Indication of giving oxygen therapy ➡ giving oxygen therapy ➡ (Monitor if SpO² fails to respond) ➡ Start intubation if there is an indication ➡ Intubation and Invasive Mechanical Ventilation Indications for oxygen therapy ➡ Oxygen therapy ➡ (Monitor if SpO² fails to respond) ➡ Considered in patients with mild-moderate degree and without hypercapnia, normal mental status, stable hemodynamics ➡